Immunobullous diseases refer to a group of blistering skin condition with an autoimmune origin. The most common of these is pemphigus vulgaris and bullous pemphigoid. … Pemphigus vulgaris is a blistering disease that appears most commonly on mucosal surfaces such as the mouth, nose, eye, and genital area.

Bullous Pemphigoid is the most common autoimmune blistering disorder and usually occurs in the elderly (over age 60). Lesions usually present with itching, pink patches or whelp like lesions that canmimic eczema or urticaria. They usually eventually form tense fluid filled vesicles on the surface. Involvement of the lower abdomen, groin, and inner arms and legs. These disorders can become serious and should be seen promptly by a board-certified Dermatologist to accurately diagnose the problem and institute treatment.