Over time, natural fat begins to deteriorate, resulting in sagging skin, more prominent wrinkles and a reduction of volume. Restylane Lyft, formerly known as Perlane-L®, is an injectable hyaluronic acid gel used to correct volume loss and treat wrinkles in the face and hands. Through nonsurgical injections, Lyft is specifically designed to add fullness to the cheeks, midface area, and the back of the hands.